To test the effectiveness of a collaborative depression care model in improving depression and hepatitis C virus () care.
Hepatitis C virus clinic patients who screened positive for depression at four Veterans Affairs Hospitals.
We compared off‐site depression collaborative care (delivered by depression care manager, pharmacist, and psychiatrist) with usual care in a randomized trial. Primary depression outcomes were treatment response (≥50 percent decrease in 20‐item Hopkins Symptoms Checklist [‐20] score), remission (mean ‐20 score, <0.5), and depression‐free days (s). Primary outcome was receipt of treatment.
Patient data were collected by self‐report telephone surveys at baseline and 12 months, and from electronic medical records.
Baseline screening identified 292 ‐infected patients with depression, and 242 patients completed 12‐month follow‐up (82.9 percent). Intervention participants were more likely to report depression treatment response, remission, and more s than usual care participants. Intervention participants were more likely to receive antiviral treatment; however, the difference was not statistically significant.
Off‐site depression collaborative care improved depression outcomes in patients and may serve as a model for collaboration between mental health and specialty physical health providers in other high co‐occurring conditions.
Data Sources/Study Setting