Volume 53 | Number 4 | August 2018

Abstract List

Fasiha Kanwal M.D., M.S.H.S., Jeffrey M. Pyne M.D., Shahriar Tavakoli‐Tabasi M.D., Susan Nicholson P.A.‐C., Brian Dieckgraefe M.D., Ph.D., Erma Storay M.S.N., A.P.N.‐B.C., Matthew Bidwell Goetz M.D., Jennifer R. Kramer Ph.D., M.P.H., Donna Smith M.Ed., Shubhada Sansgiry Ph.D., Aylin Tansel M.D., Allen L. Gifford M.D., Steven M. Asch M.D., M.P.H.


To test the effectiveness of a collaborative depression care model in improving depression and hepatitis C virus () care.

Data Sources/Study Setting

Hepatitis C virus clinic patients who screened positive for depression at four Veterans Affairs Hospitals.

Study Design

We compared off‐site depression collaborative care (delivered by depression care manager, pharmacist, and psychiatrist) with usual care in a randomized trial. Primary depression outcomes were treatment response (≥50 percent decrease in 20‐item Hopkins Symptoms Checklist [‐20] score), remission (mean ‐20 score, <0.5), and depression‐free days (s). Primary outcome was receipt of treatment.

Data Collection

Patient data were collected by self‐report telephone surveys at baseline and 12 months, and from electronic medical records.

Principal Findings

Baseline screening identified 292 ‐infected patients with depression, and 242 patients completed 12‐month follow‐up (82.9 percent). Intervention participants were more likely to report depression treatment response, remission, and more s than usual care participants. Intervention participants were more likely to receive antiviral treatment; however, the difference was not statistically significant.


Off‐site depression collaborative care improved depression outcomes in patients and may serve as a model for collaboration between mental health and specialty physical health providers in other high co‐occurring conditions.